Complex-I-ty in aging

The Mitochondrial Complex(I)ty of Cancer

Recent evidence highlights that the cancer cell energy requirements vary greatly from normal cells and that cancer cells exhibit different metabolic phenotypes with variable participation of both glycolysis and oxidative phosphorylation. NADH-ubiquinone oxidoreductase (Complex I) is the largest complex of the mitochondrial electron transport chain and contributes about 40% of the proton motive ...

Does Contact Lead to Simi lar i ty or Simi lar i ty to Contact ? 1

Evidence from the Finnish Twin Registry (e.g., Rose et al., 1988) shows that adult monozygotic (MZ) twins are more similar, within pairs, in personality if the cotwins are presently cohabiting or in frequent contact than if they are seldom in contact. Results of a follow-up study led Kaprio et al. (1990) to conclude that "'changes in social contact between monozygotic cotwins precede (and causa...

His tocompat ib i l i ty Complex - l inked I m m u n e Response Genes BY ALAN

Dest Ined for Equal I Ty

Adipos i ty and Sex Hormones in Postmenopausal Breast Cancer

Purpose: Overweight and obese women with breast cancer have poorer survival compared with thinner women. One possible reason is that breast cancer survivors with higher degrees of adiposity have higher concentrations of tumor-promoting hormones. This study examined the association between adiposity and concentrations of estrogens, androgens, and sex hormone–binding globulin (SHBG) in a populati...